Gene_name | Experimentally Verified Resistance Gene Information | Predicted Resistance Gene Information |
modA | BacMet ID: BAC0598Code for:
Binding proteinFamily: ABC superfamily, bacterial solute-binding protein ModA family.Sequence: FASTACross-database IDs: LinkOrganism: Desulfovibrio vulgaris Hildenborough (strain GZ6027)Location:
ChromosomeCompound: Tungsten (W), Molybdenum (Mo)Description: Molybdenum ABC transporter, periplasmic molybdenum-binding protein. Part of the ModABC transport system.Length (amino acid):
269Reference: Kazarov et al. 2013; Pubmed- 23913324
| Similar
resistance genes in 'BacMet Predicted database' |
modA | BacMet ID: BAC0609Code for:
Binding proteinFamily: ABC superfamily, bacterial solute-binding protein ModA family.Sequence: FASTACross-database IDs: LinkOrganism: Escherichia coli (strain K12)Location:
ChromosomeCompound: Tungsten (W), Molybdenum (Mo)Description: Molybdate-binding periplasmic protein. Involved in the transport of molybdenum into the cell. Binds molybdate with high specificity and affinity.Length (amino acid):
257Reference: Rech et al. 1995; Pubmed- 7860583, Walkenhorst et al. 1995; Pubmed- 8564363
| Similar
resistance genes in 'BacMet Predicted database' |
modB | BacMet ID: BAC0599Code for:
EnzymeFamily: ABC superfamily, binding-protein-dependent transport system permease family. CysTW subfamilySequence: FASTACross-database IDs: LinkOrganism: Desulfovibrio vulgaris Hildenborough (strain GZ6027)Location:
ChromosomeCompound: Tungsten (W), Molybdenum (Mo)Description: Molybdenum ABC transporter, permease protein. Part of the ModABC transport system. Responsible for the translocation of the substrate across the membrane. modB gene encodes the integral membrane protein ModB, which builds the membrane channel of the ModABC transporter.Length (amino acid):
233Reference: Kazarov et al. 2013; Pubmed- 23913324
| Similar
resistance genes in 'BacMet Predicted database' |
modB | BacMet ID: BAC0610Code for:
EnzymeFamily: ABC superfamily, binding-protein-dependent transport system permease family. CysTW subfamilySequence: FASTACross-database IDs: LinkOrganism: Escherichia coli (strain K12)Location:
ChromosomeCompound: Tungsten (W), Molybdenum (Mo)Description: Molybdenum transport system permease protein ModB. Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.Length (amino acid):
229Reference: Rech et al. 1995; Pubmed- 7860583, Walkenhorst et al. 1995; Pubmed- 8564363
| Similar
resistance genes in 'BacMet Predicted database' |
modC | BacMet ID: BAC0600Code for:
EnzymeFamily: ABC superfamily, Molybdate importer familySequence: FASTACross-database IDs: LinkOrganism: Desulfovibrio vulgaris Hildenborough (strain GZ6027)Location:
ChromosomeCompound: Tungsten (W), Molybdenum (Mo)Description: Molybdenum ABC transporter, ATPase subunit of the ModABC complex. Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.Length (amino acid):
253Reference: Kazarov et al. 2013; Pubmed- 23913324
| Similar
resistance genes in 'BacMet Predicted database' |
modC | BacMet ID: BAC0611Code for:
EnzymeFamily: ABC transporter superfamily. Molybdate importer familySequence: FASTACross-database IDs: LinkOrganism: Escherichia coli (strain K12)Location:
ChromosomeCompound: Tungsten (W), Molybdenum (Mo)Description: Molybdenum import ATP-binding protein ModC. Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.Length (amino acid):
352Reference: Rech et al. 1995; Pubmed- 7860583, Walkenhorst et al. 1995; Pubmed- 8564363
| Similar
resistance genes in 'BacMet Predicted database' |
modE | BacMet ID: BAC0608Code for:
RegulatorFamily: ModE familySequence: FASTACross-database IDs: LinkOrganism: Escherichia coli (strain K12)Location:
ChromosomeCompound: Tungsten (W), Molybdenum (Mo)Description: Transcriptional regulator ModE. The ModE-Mo complex acts as a repressor of the modABC operon, involved in the transport of molybdate. It controls tungstate and molybdate homeostasis in bacteria.Length (amino acid):
262Reference: Rech et al. 1995; Pubmed- 7860583, Walkenhorst et al. 1995; Pubmed- 8564363, Grunden et al. 1996; Pubmed- 8550508
| Similar
resistance genes in 'BacMet Predicted database' |
perO | BacMet ID: BAC0612Code for:
EnzymeFamily: ArsB/NhaD permeases familySequence: FASTACross-database IDs: LinkOrganism: Rhodobacter capsulatusLocation:
ChromosomeCompound: Molybdenum (Mo), Tungsten (W), Vanadium (V)Description: PerO is involved in molybdate uptake. In addition to importing molybdate, PerO probably importssulfate, tungstate, and vanadate.Length (amino acid):
595Reference: Gisin et al. 2010; Pubmed- 20851900
| Similar
resistance genes in 'BacMet Predicted database' |
tunR | BacMet ID: BAC0601Code for:
RegulatorFamily: TunR familySequence: FASTACross-database IDs: LinkOrganism: Desulfovibrio vulgaris Hildenborough (strain GZ6027)Location:
ChromosomeCompound: Tungsten (W), Molybdenum (Mo)Description: Tungstate-responsive regulator, TunR. It controls tungstate and molybdate homeostasis in sulfate-reducing deltaproteobacteria. TunR functions as an activator of the modA, modBC, and tunR genes in the absence of tungstate and repressed by tungstate. Regulates the ModABC transport system in Desulfovibrio spp.Length (amino acid):
403Reference: Kazarov et al. 2013; Pubmed- 23913324
| Similar
resistance genes in 'BacMet Predicted database' |
wtpA | BacMet ID: BAC0602Code for:
Binding proteinFamily: ABC superfamilySequence: FASTACross-database IDs: LinkOrganism: Pyrococcus furiosusLocation:
ChromosomeCompound: Tungsten (W), Molybdenum (Mo)Description: Molybdate/tungstate-binding protein WtpA. Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate, with a preference for tungstate.Length (amino acid):
345Reference: Bevers et al. 2006; Pubmed- 16952940
| Similar
resistance genes in 'BacMet Predicted database' |
wtpB | BacMet ID: BAC0603Code for:
EnzymeFamily: ABC superfamily, binding-protein-dependent transport system permease familySequence: FASTACross-database IDs: LinkOrganism: Pyrococcus furiosusLocation:
ChromosomeCompound: Tungsten (W), Molybdenum (Mo)Description: Molybdate/tungstate transport system permease protein WtpB. Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Probably responsible for the translocation of the substrate across the membrane.Length (amino acid):
249Reference: Bevers et al. 2006; Pubmed- 16952940
| Similar
resistance genes in 'BacMet Predicted database' |
wtpC | BacMet ID: BAC0604Code for:
EnzymeFamily: ABC transporter superfamily. ATPase familySequence: FASTACross-database IDs: LinkOrganism: Pyrococcus furiosusLocation:
ChromosomeCompound: Tungsten (W), Molybdenum (Mo)Description: Molybdate/tungstate import ATP-binding protein WtpC (ATPase). Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Responsible for energy coupling to the transport system.Length (amino acid):
344Reference: Bevers et al. 2006; Pubmed- 16952940
| Similar
resistance genes in 'BacMet Predicted database' |
yieF | BacMet ID: BAC0541Code for:
EnzymeFamily: SsuE familySequence: FASTACross-database IDs: LinkOrganism: Escherichia coli K12Location:
ChromosomeCompound: Chromium (Cr), Vanadium (V), Molybdenum (Mo), Methylene Blue [class: Thiazinium]Description: A chromate reductase. Reduces chromate (Cr(VI)) to Cr(III) Length (amino acid):
188Reference: Ackerley et al. 2004; Pubmed- 14766567
| Similar
resistance genes in 'BacMet Predicted database' |